SCHEMBL1930728

SCHEMBL1930728

CCOC(=O)C[C@H](NCCC[Si](C)(OC)OC)C(=O)OCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
TSHR P16473 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
GAA P10253 2/20 0.34
MGAM O43451 1/20 0.34
SI P14410 1/20 0.34
MGAM2 Q2M2H8 1/20 0.34
CHRM1 P11229 1/20 0.34
ADORA1 P30542 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56140 0.87 KMT2A (0.38) KMT2APOLBL3MBTL1ALDH1A1CYP3A4
SCHEMBL196288 0.87 KMT2A (0.38) KMT2APOLBL3MBTL1ALDH1A1CYP3A4
SCHEMBL31042769 0.84 CA12 (0.30)
SCHEMBL26372509 0.82 KMT2A (0.33) KMT2APOLBL3MBTL1ALDH1A1CYP3A4
SCHEMBL13791979 0.82 KMT2A (0.47) KMT2APOLBL3MBTL1ALDH1A1CYP3A4
SCHEMBL31121509 0.82 KMT2A (0.47) KMT2APOLBL3MBTL1ALDH1A1CYP3A4
SCHEMBL1931815 0.82 KMT2A (0.38) KMT2APOLBL3MBTL1ALDH1A1CYP3A4
SCHEMBL1931813 0.82 KMT2A (0.38) KMT2APOLBL3MBTL1ALDH1A1CYP3A4
SCHEMBL11905390 0.81
SCHEMBL5474645 0.81 KMT2A (0.47) KMT2APOLBL3MBTL1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305107-A1 AGING-RESISTANT MOISTURE-CURING COMPOSITIONS Covestro Deutschland AG (DE) 2024-01-17 EP disclosed
WO-2022189382-A1 AGING-RESISTANT MOISTURE-CURING COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2022-09-15 WO disclosed
US-8431674-B2 Polyester prepolymers BAYER MATERIALSCIENCE AG (DE) 2013-04-30 US disclosed
US-20120245242-A1 POLYURETHANE PREPOLYMERS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-09-27 US disclosed
US-20110130512-A1 POLYESTER PREPOLYMERS BAYER MATERIALSCIENCE AG (DE) 2011-06-02 US disclosed
US-7812087-B2 Polyurethane prepolymers containing alkoxysilane groups and allophanate and/or biuret groups BAYER MATERIALSCIENCE AG (DE) 2010-10-12 US disclosed
US-20080293908-A1 Polyester Prepolymers BAYER MATERIALSCIENCE AG (DE) 2008-11-27 US disclosed
US-20070055010-A1 Polyurethane prepolymers containing alkoxysilane groups and allophanate and/or biuret groups BAYER MATERIALSCIENCE AG 2007-03-08 US disclosed