SCHEMBL1931815

SCHEMBL1931815

CCOC(=O)C[C@H](NCCC[Si](OCC)(OCC)OCC)C(=O)OCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
GAA P10253 3/20 0.35
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTT P42858 1/20 0.34
ALDH1A1 P00352 6/20 0.33
CYP3A4 P08684 2/20 0.33
ALOX15 P16050 2/20 0.33
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 2/20 0.32
CHRM1 P11229 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931813 1.00 KMT2A (0.38) KMT2APOLBL3MBTL1GAAMGAM
SCHEMBL26372535 0.91 KMT2A (0.35) KMT2APOLBL3MBTL1GAAMGAM
SCHEMBL15999304 0.90 GAA (0.34) KMT2APOLBL3MBTL1GAAMGAM
SCHEMBL17505034 0.89 SMN1; SMN2 (0.35) KMT2APOLBL3MBTL1SMN1; SMN2CAD
SCHEMBL196288 0.89 KMT2A (0.38) KMT2APOLBL3MBTL1GAAMGAM
SCHEMBL56140 0.89 KMT2A (0.38) KMT2APOLBL3MBTL1GAAMGAM
SCHEMBL26458075 0.87 KMT2A (0.35) KMT2APOLBL3MBTL1GAAMGAM
SCHEMBL4452598 0.87 MAPT (0.35) L3MBTL1ALDH1A1TSHRSMN1; SMN2HSD17B10
SCHEMBL4452594 0.87 MAPT (0.35) L3MBTL1ALDH1A1TSHRSMN1; SMN2HSD17B10
SCHEMBL4447146 0.86 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957417-B2 Fast cure aspartate polysiloxane hybrid coating COVESTRO LLC (US) 2018-05-01 US claimed
EP-2970716-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING Covestro LLC (US) 2016-01-20 EP claimed
US-20150291846-A1 Fast Cure Aspartate Polysiloxane Hybrid Coating COVESTRO LLC 2015-10-15 US claimed
US-9085712-B2 Fast cure aspartate polysiloxane hybrid coating BAYER MATERIALSCIENCE LLC (US) 2015-07-21 US claimed
WO-2014159307-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING BAYER MATERIALSCIENCE LLC (US) 2014-10-02 WO claimed
US-20140272424-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING COVESTRO LLC 2014-09-18 US claimed
JP-6211879-A None JP disclosed
EP-3873959-B1 MULTILAYER VARNISH STRUCTURE WITH IMPROVED LAYER ADHESION COVESTRO DEUTSCHLAND AG (DE) 2024-09-11 EP disclosed
US-20240174788-A1 Aging-Resistant Moisture-Curing Compositions COVESTRO DEUTSCHLAND AG (DE) 2024-05-30 US disclosed
EP-4305107-A1 AGING-RESISTANT MOISTURE-CURING COMPOSITIONS Covestro Deutschland AG (DE) 2024-01-17 EP disclosed
EP-3732223-B1 ALKOXYSILANE MODIFIED POLYUREA COMPOUNDS BASED ON A MIXTURE OF DIALKOXY AND TRIALKOXYSILANES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-09-06 EP disclosed
US-11739212-B2 Alkoxy-silane-modified polyurea compounds based on a mixture of dialkoxy and trialkoxy silanes COVESTRO DEUTSCHLAND AG (DE) 2023-08-29 US disclosed
WO-2022189382-A1 AGING-RESISTANT MOISTURE-CURING COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2022-09-15 WO disclosed
US-5998504-A PROTECTIVE POLYURETHANE COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-07 US disclosed
US-5908948-A ORGANOSILICON COMPOUNDS; COATINGS, SEALANTS, ADHESIVES BAYER CORPORATION (US) 1999-06-01 US disclosed
EP-0913402-A1 Compounds containing alkoxysilane groups and hydantoin groups BAYER AG (DE) 1999-05-06 EP disclosed
EP-0864575-A2 Compounds containing urea and alkoxysilane groups Bayer Corporation (US) 1998-09-16 EP disclosed
US-5756751-A MOISTURE CURABLE COATINGS, ADHESIVES, SEALS BAYER AKTIENGESELLSCHAFT (DE) 1998-05-26 US disclosed
US-5364955-A Compounds containing alkoxysilane and amino groups BAYER AKTIENGESELLSCHAFT (DE) 1994-11-15 US disclosed
JP-H06211879-A COMPOUND CONTAINING ALKOXYSILANE AND AMINO GROUP BAYER AG 1994-08-02 JP disclosed