Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 8/20 | 0.51 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 5/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18712664 | 0.97 | SSTR2 (0.50) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL18712684 | 0.88 | SSTR2 (0.54) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL18712392 | 0.85 | SSTR2 (0.54) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL18712686 | 0.83 | SSTR2 (0.54) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL19542333 | 0.83 | SSTR2 (0.52) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL18712394 | 0.82 | SSTR2 (0.54) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL19308273 | 0.82 | SSTR2 (0.54) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL19308237 | 0.81 | SSTR2 (0.45) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL18712398 | 0.80 | SSTR2 (0.53) | SSTR2SSTR3SSTR5SSTR1SSTR4 | |
| SCHEMBL18712662 | 0.78 | SSTR2 (0.52) | SSTR2SSTR3SSTR5SSTR1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9750818-B2 | Targeted conjugates and particles and formulations thereof | TARVEDA THERAPEUTICS, INC. (US) | 2017-09-05 | — | — | US | disclosed |