SCHEMBL18712662

SCHEMBL18712662

C[C@@H](O)[C@@H]1NC[C@H](CCCCN)NC[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCCCNC(=O)CCS)NC(=O)[C@H](Cc2ccccc2)NC1=O

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SSTR2 P30874 14/20 0.52
▸ SSTR5 P35346 14/20 0.52
▸ SSTR4 P31391 12/20 0.52
▸ SSTR3 P32745 10/20 0.52
▸ SSTR1 P30872 8/20 0.52
▸ TACR2 P21452 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19308273 0.96 SSTR2 (0.54) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL17404637 0.85 SSTR4 (0.66) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL18712360 0.85 SSTR4 (0.65) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL21892348 0.83 SSTR4 (0.62) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL18712664 0.82 SSTR2 (0.50) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL21892075 0.80 SSTR5 (0.56) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL29403678 0.79 SSTR4 (0.59) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL19308189 0.78 SSTR2 (0.51) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL29356129 0.77 SSTR4 (0.65) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL10827586 0.77 SSTR5 (0.68) SSTR2SSTR5SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170095569-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF TVA (ABC), LLC 2017-04-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170095569-A1 TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF SSTR5, SSTR1, SSTR4 SSTR2 4/4885SSTR5 1/4885SSTR4 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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