SCHEMBL19308257

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(=O)NCCCN2C(=O)C=CC2=O)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O

nearest known ligand 0.52

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	SSTR2	P30874	17/20	0.52

▸	SSTR5	P35346	14/20	0.50

▸	SSTR3	P32745	13/20	0.50

▸	SSTR4	P31391	12/20	0.50

▸	SSTR1	P30872	9/20	0.50

▸	KDM4A	O75164	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21892353	0.95	SSTR2 (0.52)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL18712536	0.95	SSTR2 (0.56)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL21099575	0.95	SSTR2 (0.55)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL18712669	0.94	SSTR2 (0.49)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL17404771	0.90	SSTR2 (0.56)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL19542498	0.90	SSTR2 (0.47)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL18712668	0.89	SSTR2 (0.52)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL29897024	0.87	SSTR2 (0.59)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL17404627	0.87	SSTR2 (0.59)	SSTR2SSTR5SSTR3SSTR4SSTR1
SCHEMBL19543819	0.87	SSTR2 (0.59)	SSTR2SSTR5SSTR3SSTR4SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9750818-B2	Targeted conjugates and particles and formulations thereof	TARVEDA THERAPEUTICS, INC. (US)	2017-09-05	—	—	US	disclosed