SCHEMBL21892353

SCHEMBL21892353

C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(=O)N[C@@H](CCC(=O)NCCCN2C(=O)C=CC2=O)C(=O)NCCCN2C(=O)C=CC2=O)N(C)C(=O)[C@H](Cc2ccccc2)NC1=O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SSTR2 P30874 18/20 0.52
▸ SSTR5 P35346 15/20 0.51
▸ SSTR4 P31391 14/20 0.51
▸ SSTR3 P32745 12/20 0.51
▸ SSTR1 P30872 9/20 0.51
▸ DRD2 P14416 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17404771 0.96 SSTR2 (0.56) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL19308257 0.95 SSTR2 (0.52) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL19542498 0.95 SSTR2 (0.47) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL18712536 0.90 SSTR2 (0.56) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL21099575 0.90 SSTR2 (0.55) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL18712669 0.89 SSTR2 (0.49) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL17404731 0.86 SSTR2 (0.56) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL18712400 0.86 SSTR2 (0.47) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL18712668 0.85 SSTR2 (0.52) SSTR2SSTR5SSTR4SSTR3SSTR1
SCHEMBL21100147 0.83 SSTR2 (0.50) SSTR2SSTR5SSTR4SSTR3SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10624967-B2 Targeted conjugates and particles and formulations thereof TARVEDA THERAPEUTICS, INC. (US) 2020-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10624967-B2 Targeted conjugates and particles and formulations thereof SSTR5, SSTR1, SSTR4 SSTR2 4/4885SSTR5 1/4885SSTR4 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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