Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079910 | 0.74 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL15184433 | 0.65 | — | — | |
| SCHEMBL22860505 | 0.65 | TSHR (0.35) | — | |
| SCHEMBL19574903 | 0.64 | CYP2D6 (0.36) | — | |
| SCHEMBL20074628 | 0.64 | — | — | |
| SCHEMBL21549978 | 0.64 | — | — | |
| SCHEMBL18972203 | 0.64 | — | — | |
| SCHEMBL18433821 | 0.63 | SLC18A3 (0.39) | — | |
| SCHEMBL25124122 | 0.63 | BIRC2 (0.31) | — | |
| SCHEMBL25946470 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751861-B2 | N1-(3,3,3-trifluoro-2-hydroxo-2-methylpropionyl)-piperidine derivatives as inhibitors of pyruvate dehydrogenase kinase | MERCK PATENT GMBH (DE) | 2017-09-05 | — | — | US | disclosed |