⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976818 | 0.83 | — | — | |
| SCHEMBL4462479 | 0.82 | — | — | |
| SCHEMBL3079746 | 0.71 | — | — | |
| SCHEMBL13483440 | 0.71 | — | — | |
| SCHEMBL23376902 | 0.71 | — | — | |
| SCHEMBL3195059 | 0.67 | — | — | |
| SCHEMBL14778061 | 0.67 | — | — | |
| SCHEMBL7170470 | 0.67 | — | — | |
| SCHEMBL6983611 | 0.65 | MEN1 (0.31) | — | |
| SCHEMBL19979162 | 0.65 | NOS3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399761-B2 | Phthalazine derivatives with angiogenesis inhibiting activity | NOVARTIS AG (CH) | 2008-07-15 | — | — | US | claimed |
| US-20040180899-A1 | Phthalazine derivatives with angiogenesis inhibiting activity | NOVARTIS AG (CH) | 2004-09-16 | — | — | US | claimed |
| EP-1387836-A1 | PHTHALAZINE DERIVATIVES WITH ANGIOGENESIS INHIBITING ACTIVITY | Novartis AG (CH) | 2004-02-11 | — | — | EP | claimed |
| WO-2002090346-A1 | PHTHALAZINE DERIVATIVES WITH ANGIOGENESIS INHIBITING ACTIVITY | NOVARTIS AG (CH) | 2002-11-14 | — | — | WO | claimed |
| US-8034814-B2 | Phthalazine derivatives with angiogenesis inhibiting activity | NOVARTIS AG (CH) | 2011-10-11 | — | — | US | disclosed |
| US-20110130399-A1 | Phthalazine Derivatives with Angiogenesis Inhibiting Activity | NOVARTIS AG (CH) | 2011-06-02 | — | — | US | disclosed |
| US-20090076003-A1 | Phthalazine Derivatives with Angiogenesis Inhibiting Activity | NOVARTIS AG | 2009-03-19 | — | — | US | disclosed |
| US-7399761-B2 | Phthalazine derivatives with angiogenesis inhibiting activity | NOVARTIS AG (CH) | 2008-07-15 | — | — | US | disclosed |
| US-20040180899-A1 | Phthalazine derivatives with angiogenesis inhibiting activity | NOVARTIS AG (CH) | 2004-09-16 | — | — | US | disclosed |
| EP-1387836-A1 | PHTHALAZINE DERIVATIVES WITH ANGIOGENESIS INHIBITING ACTIVITY | Novartis AG (CH) | 2004-02-11 | — | — | EP | disclosed |
| WO-2002090346-A1 | PHTHALAZINE DERIVATIVES WITH ANGIOGENESIS INHIBITING ACTIVITY | NOVARTIS AG (CH) | 2002-11-14 | — | — | WO | disclosed |
| US-5633268-A | FUNGICIDES, INSECTICIDES, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |
| EP-0309913-B1 | Fungicidal N-substituted 3-aryl-pyrrolidine derivatives | BASF AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| US-5068245-A | For treatment of plants | BASF AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0309913-A2 | Fungicidal N-substituted 3-aryl-pyrrolidine derivatives | BASF Aktiengesellschaft (DE) | 1989-04-05 | — | — | EP | disclosed |
| EP-0081207-A2 | Aniline derivatives, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1983-06-15 | — | — | EP | disclosed |