Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 6/20 | 0.44 |
| ▸ | PDE1A | P54750 | 4/20 | 0.44 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273193 | 0.72 | CYP11B2 (0.48) | PDE1CPDE1APDE1BCYP11B2PDE4A | |
| SCHEMBL2196349 | 0.69 | PDE1C (0.35) | PDE1CPDE1APDE1BCYP2B6 | |
| SCHEMBL2196350 | 0.69 | PDE1C (0.35) | PDE1CPDE1APDE1BCYP2B6 | |
| SCHEMBL2196608 | 0.69 | PDE1C (0.35) | PDE1CPDE1APDE1B | |
| SCHEMBL2196850 | 0.69 | PDE1C (0.35) | PDE1CPDE1APDE1BCYP2B6 | |
| SCHEMBL2195467 | 0.69 | PDE1C (0.35) | PDE1CPDE1APDE1BCYP2B6 | |
| SCHEMBL2196427 | 0.69 | PDE1C (0.35) | PDE1CPDE1APDE1B | |
| SCHEMBL2196580 | 0.69 | PDE1C (0.35) | PDE1CPDE1APDE1BCYP2B6 | |
| SCHEMBL20858655 | 0.68 | GSK3A (0.42) | KMT2A | |
| SCHEMBL1346670 | 0.68 | GRIA2 (0.42) | PDE1CPDE1APDE1BCYP11B2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751844-B2 | Precursor compound connected to solid support for manufacturing 18F radiopharmaceutical, method for manufacturing same, and application thereof | FUTURECHEM CO., LTD. (KR) | 2017-09-05 | — | — | US | disclosed |