Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 5/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.62 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915335 | 0.83 | F3 (0.73) | MAPTCYP3A4ALDH1A1BCHECYP1B1 | |
| SCHEMBL5915334 | 0.83 | F3 (0.73) | MAPTCYP3A4ALDH1A1BCHECYP1B1 | |
| SCHEMBL5915802 | 0.83 | F3 (0.73) | MAPTCYP3A4ALDH1A1BCHECYP1B1 | |
| SCHEMBL655660 | 0.83 | MAPT (0.68) | MAPTCYP3A4ALDH1A1HPGDBCHE | |
| SCHEMBL655661 | 0.83 | MAPT (0.68) | MAPTCYP3A4ALDH1A1HPGDBCHE | |
| SCHEMBL4575024 | 0.82 | HDAC6 (0.71) | CYP3A4ALDH1A1HPGDMAOBLMNA | |
| SCHEMBL4575021 | 0.82 | HDAC6 (0.71) | CYP3A4ALDH1A1HPGDMAOBLMNA | |
| SCHEMBL8431772 | 0.82 | CYP1B1 (0.91) | MAPTCYP3A4ALDH1A1HPGDBCHE | |
| SCHEMBL9915665 | 0.82 | CYP1B1 (0.91) | MAPTCYP3A4ALDH1A1HPGDBCHE | |
| SCHEMBL5915675 | 0.81 | HDAC6 (0.57) | MAPTCYP3A4ALDH1A1HPGDBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110129932-A1 | Lipoprotein Assay | L3 TECHNOLOGY LIMITED (GB) | 2011-06-02 | — | — | US | disclosed |
| EP-2041579-A2 | LIPOPROTEIN ASSAY | L3 Technology Limited (GB) | 2009-04-01 | — | — | EP | disclosed |
| WO-2007144601-A2 | LIPOPROTEIN ASSAY | L3 TECHNOLOGY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |