SCHEMBL9915665

SCHEMBL9915665

O=C(/C=C/c1ccc(/C=C/C(=O)c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1B1 Q16678 6/20 0.91
MAPT P10636 5/20 0.91
MAOB P27338 4/20 0.91
BCHE P06276 3/20 0.91
LMNA P02545 2/20 0.91
PLIN1 O60240 1/20 0.91
TNFRSF1A P19438 1/20 0.91
ACHE P22303 1/20 0.91
RECQL P46063 1/20 0.91
PLIN5 Q00G26 1/20 0.91
ABHD5 Q8WTS1 1/20 0.91
CYP3A4 P08684 4/20 0.85
KMT2A Q03164 3/20 0.85
NFKB1 P19838 2/20 0.85
NFKB2 Q00653 2/20 0.85
RELA Q04206 2/20 0.85
HSPD1 P10809 2/20 0.85
HSPE1 P61604 2/20 0.85
RAB9A P51151 2/20 0.85
PKM P14618 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8431772 1.00 CYP1B1 (0.91) CYP1B1MAPTMAOBBCHELMNA
Chalcone SCHEMBL28306720 0.95 CYP1B1 (1.00) CYP1B1MAPTMAOBBCHELMNA
Chalcone SCHEMBL29922932 0.95 CYP1B1 (1.00) CYP1B1MAPTMAOBBCHELMNA
Chalcone SCHEMBL27581 0.95 CYP1B1 (1.00) CYP1B1MAPTMAOBBCHELMNA
Chalcone SCHEMBL2404758 0.95 CYP1B1 (1.00) CYP1B1MAPTMAOBBCHELMNA
Chalcone SCHEMBL27580 0.95 CYP1B1 (1.00) CYP1B1MAPTMAOBBCHELMNA
Chalcone SCHEMBL29396001 0.95 CYP1B1 (1.00) CYP1B1MAPTMAOBBCHELMNA
Chalcone SCHEMBL454583 0.95 CYP1B1 (1.00) CYP1B1MAPTMAOBBCHELMNA
SCHEMBL25193884 0.94 CYP1B1 (0.81) CYP1B1MAPTMAOBBCHELMNA
SCHEMBL13680426 0.94 CYP1B1 (0.81) CYP1B1MAPTMAOBBCHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2164826-B1 DENDRITIC PHOTOACTIVE COMPOUND COMPRISING OXIME ESTER AND METHOD FOR PREPARING THE SAME LG CHEMICAL LTD (KR) 2013-04-03 EP disclosed
US-8198462-B2 Dendritic photoactive compound comprising oxime ester and method for preparing the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-8198462-B2 Dendritic photoactive compound comprising oxime ester and method for preparing the same LG CHEM, LTD. (KR) 2012-06-12 US disclosed
US-20100145068-A1 Dendritic Photoactive Compound Comprising Oxime Ester And Method For Preparing The Same LG CHEM, LTD. (KR) 2010-06-10 US disclosed
US-20100145068-A1 Dendritic Photoactive Compound Comprising Oxime Ester And Method For Preparing The Same LG CHEM, LTD. (KR) 2010-06-10 US disclosed
US-7582364-B2 Utilizing phosphorescence which emits light efficiently with high luminance at low current density; flat panel displays NIPPON STEEL CHEMICAL CO., LTD. (JP) 2009-09-01 US disclosed
US-7582364-B2 Utilizing phosphorescence which emits light efficiently with high luminance at low current density; flat panel displays NIPPON STEEL CHEMICAL CO., LTD. (JP) 2009-09-01 US disclosed
WO-2009011538-A2 DENDRITIC PHOTOACTIVE COMPOUND COMPRISING OXIME ESTER AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2009-01-22 WO disclosed
US-20070012935-A1 Organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2007-01-18 US disclosed
US-20070012935-A1 Organic electroluminescent device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100145068-A1 Dendritic Photoactive Compound Comprising Oxime Ester And Method For Preparing The Same PPOX, OXER1, TLR7 CYP1B1 2436/4885MAPT 612/4885MAOB 260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.