SCHEMBL4447146

SCHEMBL4447146

CCO[Si](CCCN[C@@H](CC(=O)OC)C(=O)OC)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4447143 1.00 TSHR (0.31) TSHR
SCHEMBL2020702 0.87 CA12 (0.31) TSHR
SCHEMBL4199536 0.87 CA12 (0.31) TSHR
SCHEMBL1931813 0.86 KMT2A (0.38) TSHR
SCHEMBL1931815 0.86 KMT2A (0.38) TSHR
SCHEMBL11905120 0.82
SCHEMBL13040564 0.82 CA12 (0.32) TSHR
SCHEMBL730349 0.82 CA12 (0.32)
SCHEMBL15999304 0.82 GAA (0.34)
SCHEMBL11905494 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957417-B2 Fast cure aspartate polysiloxane hybrid coating COVESTRO LLC (US) 2018-05-01 US claimed
EP-2970716-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING Covestro LLC (US) 2016-01-20 EP claimed
US-20150291846-A1 Fast Cure Aspartate Polysiloxane Hybrid Coating COVESTRO LLC 2015-10-15 US claimed
US-9085712-B2 Fast cure aspartate polysiloxane hybrid coating BAYER MATERIALSCIENCE LLC (US) 2015-07-21 US claimed
WO-2014159307-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING BAYER MATERIALSCIENCE LLC (US) 2014-10-02 WO claimed
US-20140272424-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING COVESTRO LLC 2014-09-18 US claimed
WO-2020129955-A1 MOISTURE-CURABLE HOT-MELT ADHESIVE セメダイン株式会社 2020-06-25 WO disclosed
CN-105308136-B Fast curing aspartate polysiloxane hybrid coating 科思创有限公司 2018-09-18 CN disclosed
US-9957417-B2 Fast cure aspartate polysiloxane hybrid coating COVESTRO LLC (US) 2018-05-01 US disclosed
EP-2970716-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING Covestro LLC (US) 2016-01-20 EP disclosed
US-20150291846-A1 Fast Cure Aspartate Polysiloxane Hybrid Coating COVESTRO LLC 2015-10-15 US disclosed
US-9085712-B2 Fast cure aspartate polysiloxane hybrid coating BAYER MATERIALSCIENCE LLC (US) 2015-07-21 US disclosed
WO-2014159307-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING BAYER MATERIALSCIENCE LLC (US) 2014-10-02 WO disclosed
US-20140272424-A1 FAST CURE ASPARTATE POLYSILOXANE HYBRID COATING COVESTRO LLC 2014-09-18 US disclosed
US-7635743-B2 alkoxysilane-terminated polyesterurethane copolymer was obtained in presence of bis-(N, N'-dimethylaminoethyl) ether polymerization catalyst; blocked isocyanates; stable storage at a high temperature and cures very rapidly under the atmosphere; for gluing the most diverse substrates BAYER MATERIALSCIENCE AG (DE) 2009-12-22 US disclosed
US-20060142532-A1 Moisture-curing composition and hot-melt adhesive BAYER MATERIALSCIENCE AG 2006-06-29 US disclosed
US-5998504-A PROTECTIVE POLYURETHANE COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-07 US disclosed
US-5364955-A Compounds containing alkoxysilane and amino groups BAYER AKTIENGESELLSCHAFT (DE) 1994-11-15 US disclosed