⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21403392 | 0.74 | TSHR (0.43) | — | |
| SCHEMBL905327 | 0.74 | — | — | |
| SCHEMBL7039895 | 0.70 | — | — | |
| SCHEMBL25246041 | 0.69 | — | — | |
| SCHEMBL9684749 | 0.67 | FFAR3 (0.30) | — | |
| SCHEMBL28665208 | 0.67 | TSHR (0.33) | — | |
| SCHEMBL16816935 | 0.67 | NPSR1 (0.39) | — | |
| SCHEMBL3262406 | 0.66 | ALDH1A1 (0.30) | — | |
| SCHEMBL28076495 | 0.65 | — | — | |
| SCHEMBL28022605 | 0.65 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8696952-B2 | Method of producing polymeric particles with selected size, shape, morphology and composition | KUMACHEVA EUGENIA (CA) | 2014-04-15 | — | — | US | disclosed |
| US-20110129941-A1 | Method of Producing Polymeric Particles With Selected Size, Shape, Morphology and Composition | KUMACHEVA EUGENIA | 2011-06-02 | — | — | US | disclosed |
| EP-1742979-A4 | METHOD OF PRODUCING POLYMERIC PARTICLES WITH SELECTED SIZE, SHAPE, MORPHOLOGY AND COMPOSITION | KUMACHEVA EUGENIA (CA) | 2008-05-21 | — | — | EP | disclosed |
| EP-1742979-A1 | METHOD OF PRODUCING POLYMERIC PARTICLES WITH SELECTED SIZE, SHAPE, MORPHOLOGY AND COMPOSITION | Kumacheva, Eugenia (CA) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005103106-A1 | METHOD OF PRODUCING POLYMERIC PARTICLES WITH SELECTED SIZE, SHAPE, MORPHOLOGY AND COMPOSITION | KUMACHEVA EUGENIA (CA) | 2005-11-03 | — | — | WO | disclosed |