Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19140752 | 0.81 | MAPK1 (0.44) | MAPK1KMT2AMAPTTDP1KDM4E | |
| SCHEMBL12251825 | 0.67 | ALOX5 (0.42) | ALOX5PTGS1PTGS2RXFP1CYP1A2 | |
| SCHEMBL19140899 | 0.67 | MAPK1 (0.51) | MAPK1CYP1A2CYP2C9KMT2AMAPT | |
| SCHEMBL18506668 | 0.65 | ALOX5 (0.46) | ALOX5PTGS1PTGS2RXFP1CYP1A2 | |
| SCHEMBL18506694 | 0.65 | ALOX5 (0.46) | ALOX5PTGS1PTGS2RXFP1CYP1A2 | |
| SCHEMBL19139674 | 0.65 | ALOX5 (0.46) | ALOX5PTGS1PTGS2RXFP1CYP1A2 | |
| SCHEMBL22210756 | 0.65 | ALOX5 (0.46) | ALOX5PTGS1PTGS2RXFP1CYP1A2 | |
| SCHEMBL22210771 | 0.65 | ALOX5 (0.46) | ALOX5PTGS1PTGS2RXFP1CYP1A2 | |
| SCHEMBL21573718 | 0.65 | ALOX5 (0.46) | ALOX5PTGS1PTGS2RXFP1CYP1A2 | |
| SCHEMBL18506667 | 0.65 | ALOX5 (0.46) | ALOX5PTGS1PTGS2RXFP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | CRHBP 1463/4885CRHR2 1074/4885HIF1A 2699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.