Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19320878 | 1.00 | MEN1 (0.46) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19320876 | 0.96 | MAPT (0.44) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19325607 | 0.88 | MEN1 (0.46) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19325604 | 0.88 | MEN1 (0.46) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19325792 | 0.85 | MAPT (0.44) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19321474 | 0.84 | PTPN1 (0.41) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19320879 | 0.84 | ESR1 (0.35) | MEN1KMT2AALDH1A1RAB9APTGS2 | |
| SCHEMBL19320875 | 0.82 | CACNA1G (0.47) | ALDH1A1LMNAHTTSMN1; SMN2CNR2 | |
| SCHEMBL19320826 | 0.82 | CACNA1G (0.47) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL19320828 | 0.81 | CNR2 (0.39) | ALDH1A1PTGS2LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | MEN1 4668/4885KMT2A 1478/4885ALDH1A1 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.