Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | IAPP | P10997 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187685 | 0.89 | CYP1A2 (0.38) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL27669219 | 0.89 | CNR2 (0.38) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL19335916 | 0.88 | GAA (0.43) | GAAKMT2AMEN1MAOBMAOA | |
| SCHEMBL8773778 | 0.88 | NPC1 (0.40) | CYP3A4GAAKMT2AF2RCNR2 | |
| SCHEMBL2464472 | 0.88 | NPC1 (0.40) | CYP3A4GAAKMT2AF2RCNR2 | |
| SCHEMBL30485788 | 0.88 | NPC1 (0.40) | CYP3A4GAAKMT2AF2RCNR2 | |
| SCHEMBL23533531 | 0.86 | CNR2 (0.41) | GAAKMT2AMEN1MAOBMAOA | |
| SCHEMBL7749752 | 0.86 | KMT2A (0.55) | GAAKMT2AMEN1MAOBMAOA | |
| SCHEMBL5630244 | 0.86 | CNR2 (0.41) | GAAKMT2AMEN1MAOBMAOA | |
| SCHEMBL9879512 | 0.86 | KMT2A (0.55) | GAAKMT2AMEN1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110130492-A1 | STABILIZATION OF POLYETHER POLYOL, POLYESTER POLYOL OR POLYURETHANE COMPOSITIONS | MAEDER DIETMAR | 2011-06-02 | — | — | US | disclosed |