Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30485788 | 1.00 | NPC1 (0.40) | NPC1RAB9APTGS2LMNACYP3A4 | |
| SCHEMBL2464472 | 1.00 | NPC1 (0.40) | NPC1RAB9APTGS2LMNACYP3A4 | |
| SCHEMBL2955109 | 0.95 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL7701744 | 0.91 | CNR2 (0.38) | NPC1RAB9ALMNAF2RCNR2 | |
| SCHEMBL13324689 | 0.90 | NPC1 (0.44) | NPC1RAB9ALMNAF2RPOLB | |
| SCHEMBL6516967 | 0.89 | NPC1 (0.41) | NPC1RAB9ALMNACYP3A4POLB | |
| SCHEMBL4824480 | 0.89 | NPC1 (0.38) | NPC1RAB9APTGS2LMNACYP3A4 | |
| SCHEMBL8861271 | 0.89 | NPC1 (0.38) | NPC1RAB9APTGS2LMNACYP3A4 | |
| SCHEMBL8861274 | 0.89 | NPC1 (0.38) | NPC1RAB9APTGS2LMNACYP3A4 | |
| SCHEMBL1932289 | 0.88 | CYP1A2 (0.41) | NPC1RAB9ALMNACYP3A4F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5675015-A | Process for the preparation of benzotriazole derivatives | EASTMAN KODAK COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0794179-A1 | Process for the preparation of benzotriazole derivatives | EASTMAN KODAK COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0036117-B1 | PRESSURE-SENSITIVE RECORDING MATERIAL | Spezial-Papiermaschinenfabrik August Alfred Krupp GmbH & Co (DE) | 1986-02-05 | — | — | EP | disclosed |
| EP-0036117-A2 | Pressure-sensitive recording material | Spezial-Papiermaschinenfabrik August Alfred Krupp GmbH & Co (DE) | 1981-09-23 | — | — | EP | disclosed |