Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 6/20 | 0.53 |
| ▸ | FABP7 | O15540 | 4/20 | 0.53 |
| ▸ | FABP3 | P05413 | 3/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15064397 | 1.00 | FABP5 (0.53) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL12556037 | 1.00 | FABP5 (0.53) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL15083015 | 1.00 | FABP5 (0.53) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL1932636 | 0.94 | FABP5 (0.48) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL6858142 | 0.82 | FABP5 (0.58) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL9370830 | 0.82 | FABP5 (0.58) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL28635740 | 0.81 | FABP5 (0.57) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL28635739 | 0.81 | FABP5 (0.57) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL7433044 | 0.81 | FABP5 (0.57) | FABP5FABP7FABP3SLC18A3TACR1 | |
| SCHEMBL28644515 | 0.81 | FABP5 (0.57) | FABP5FABP7FABP3SLC18A3TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172553-A1 | CHIRAL SYNTHESIS OF ISOXAZOLINES, ISOXAZOLINE COMPOUNDS, AND USES THEREOF | CPSI STOCKHOLDER TRUST (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172553-A1 | CHIRAL SYNTHESIS OF ISOXAZOLINES, ISOXAZOLINE COMPOUNDS, AND USES THEREOF | CPSI STOCKHOLDER TRUST (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172553-A1 | CHIRAL SYNTHESIS OF ISOXAZOLINES, ISOXAZOLINE COMPOUNDS, AND USES THEREOF | CPSI STOCKHOLDER TRUST (US) | 2013-07-04 | — | — | US | disclosed |
| WO-2011066482-A2 | CHIRAL SYNTHESIS OF ISOXAZOLINES, ISOXAZOLINE COMPOUNDS, AND USES THEREOF | CYTOKINE PHARMASCIENCES, INC. (US) | 2011-06-03 | — | — | WO | disclosed |
| WO-2011066482-A2 | CHIRAL SYNTHESIS OF ISOXAZOLINES, ISOXAZOLINE COMPOUNDS, AND USES THEREOF | CYTOKINE PHARMASCIENCES, INC. (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172553-A1 | CHIRAL SYNTHESIS OF ISOXAZOLINES, ISOXAZOLINE COMPOUNDS, AND USES THEREOF | CYP3A7, CYP2A7, UGT1A7 | FABP5 3497/4885FABP7 1058/4885FABP3 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.