Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB7A | P51149 | 5/20 | 0.59 |
| ▸ | SLC34A2 | O95436 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321159 | 0.92 | RAB7A (0.60) | RAB7ASLC34A2MEN1KMT2ANPC1 | |
| SCHEMBL19325776 | 0.89 | RAB7A (0.61) | RAB7AMEN1KMT2ANPC1MAPT | |
| SCHEMBL19326363 | 0.86 | RAB7A (0.52) | RAB7ASLC34A2MEN1KMT2ANPC1 | |
| SCHEMBL21247382 | 0.84 | RAB7A (0.80) | RAB7AMEN1KMT2ANPC1MAPT | |
| SCHEMBL19326139 | 0.81 | RAB7A (0.49) | RAB7AMEN1KMT2ANPC1MAPT | |
| SCHEMBL19326206 | 0.81 | RAB7A (0.55) | RAB7AMEN1KMT2ANPC1MAPT | |
| SCHEMBL19325636 | 0.81 | RAB7A (0.59) | RAB7AMEN1KMT2ANPC1MAPT | |
| SCHEMBL19325850 | 0.81 | RAB7A (0.44) | RAB7ASLC34A2KMT2ANPC1MAPT | |
| SCHEMBL19326367 | 0.81 | RAB7A (0.49) | RAB7ASLC34A2MEN1KMT2ANPC1 | |
| SCHEMBL19325820 | 0.81 | RAB7A (0.54) | RAB7AMEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | RAB7A 1008/4885SLC34A2 1471/4885MEN1 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.