Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15166835 | 0.80 | P2RX7 (0.33) | P2RX7MAPK1 | |
| SCHEMBL15185767 | 0.78 | P2RX7 (0.31) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL18929485 | 0.73 | P2RX7 (0.37) | P2RX7MAPK1P4HBLPLLIPG | |
| SCHEMBL18696943 | 0.73 | P2RX7 (0.37) | P2RX7MAPK1P4HBLPLLIPG | |
| SCHEMBL25136361 | 0.72 | MAPK1 (0.46) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL18095998 | 0.72 | P2RX7 (0.48) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL31570487 | 0.70 | P2RX7 (0.47) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL30708588 | 0.70 | P2RX7 (0.43) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL15166628 | 0.70 | P2RX7 (0.34) | P2RX7MAPK1 | |
| SCHEMBL30965862 | 0.67 | P2RX7 (0.47) | P2RX7MAPK1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814834-B1 | C-3 CYCLOALKENYL TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | VIIV HEALTHCARE UK (NO 5) LTD (GB) | 2017-09-13 | — | — | EP | disclosed |