Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 14/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SQLE | Q14534 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906974 | 0.93 | CXCR4 (0.37) | CXCR4CXCL12KDM4ESQLEALDH1A1 | |
| SCHEMBL4906971 | 0.90 | CXCR4 (0.35) | CXCR4CXCL12KDM4ESQLE | |
| SCHEMBL14519144 | 0.89 | KDM4E (0.34) | CXCR4KDM4ESQLEALDH1A1 | |
| SCHEMBL56457 | 0.89 | KDM4E (0.42) | CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL15360533 | 0.84 | CXCR4 (0.42) | CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL19549 | 0.80 | CA12 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL5711364 | 0.80 | CA12 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL5891867 | 0.80 | CA12 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL556033 | 0.79 | KDM4E (0.45) | CXCR4KDM4EALDH1A1 | |
| SCHEMBL730245 | 0.79 | CXCR4 (0.37) | CXCR4CXCL12KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2145928-B1 | Dispersion made of hydrophobic silicon dioxide particles and granulate made from same | EVONIK DEGUSSA GMBH (DE) | 2017-09-13 | — | — | EP | disclosed |