Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841107 | 0.97 | CXCR4 (0.37) | CXCR4KDM4EALDH1A1CXCL12CYP1A2 | |
| SCHEMBL132342 | 0.92 | CXCR4 (0.40) | CXCR4KDM4EALDH1A1CXCL12CYP1A2 | |
| SCHEMBL56457 | 0.89 | KDM4E (0.42) | CXCR4KDM4EALDH1A1CXCL12HRH4 | |
| SCHEMBL15367114 | 0.87 | ALDH1A1 (0.42) | CXCR4KDM4EALDH1A1CXCL12CYP1A2 | |
| SCHEMBL16792518 | 0.85 | KDM4E (0.31) | CXCR4KDM4EALDH1A1 | |
| SCHEMBL15360533 | 0.83 | CXCR4 (0.42) | CXCR4KDM4EALDH1A1CXCL12HRH4 | |
| SCHEMBL555892 | 0.82 | KDM4E (0.41) | CXCR4KDM4EALDH1A1CXCL12CYP1A2 | |
| SCHEMBL32678386 | 0.81 | CXCR4 (0.39) | CXCR4KDM4EALDH1A1CXCL12CYP1A2 | |
| SCHEMBL32678387 | 0.81 | CXCR4 (0.39) | CXCR4KDM4EALDH1A1CXCL12CYP1A2 | |
| SCHEMBL778037 | 0.81 | CXCR4 (0.39) | CXCR4KDM4EALDH1A1CXCL12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393861-B1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-10-23 | — | — | EP | claimed |
| US-8138297-B2 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-20 | — | — | US | claimed |
| US-20100204384-A1 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-08-12 | — | — | US | claimed |
| EP-2393861-B1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8138297-B2 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20100204384-A1 | Moisture-curable silylated polymer possessing improved storage stability | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-08-12 | — | — | US | disclosed |