SCHEMBL19327445

SCHEMBL19327445

c1cnc2[nH]cc(CN3CCCCC3)c2c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 9/20 0.73
DRD3 P35462 7/20 0.73
DRD2 P14416 6/20 0.73
HTR2A P28223 7/20 0.65
HTR7 P34969 6/20 0.65
HTR1A P08908 4/20 0.65
MAPK1 P28482 3/20 0.65
HTR6 P50406 3/20 0.65
CYP1A2 P05177 2/20 0.65
CYP3A4 P08684 2/20 0.65
CYP2D6 P10635 2/20 0.65
TSHR P16473 2/20 0.65
NFKB1 P19838 2/20 0.65
HIF1A Q16665 2/20 0.65
THPO P40225 1/20 0.65
CACNA1F O60840 1/20 0.65
ADRA2A P08913 1/20 0.65
ALOX15 P16050 1/20 0.65
ADRA2B P18089 1/20 0.65
ADRA2C P18825 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5917818 0.87 DRD4 (0.71) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL32669452 0.86 DRD4 (0.63) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL6363395 0.86 DRD4 (0.63) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL857712 0.86 DRD4 (0.74) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL5198732 0.85 ALDH1A1 (0.65) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL5399421 0.85 DRD4 (1.00) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL8858021 0.85 DRD4 (0.77) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL32669409 0.84 DRD4 (0.64) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL5198686 0.82 DRD4 (1.00) DRD4DRD3DRD2HTR2AHTR7
SCHEMBL5382639 0.81 DRD4 (0.76) DRD4DRD3DRD2HTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240245670-A1 DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES NOVARTIS AG (CH) 2024-07-25 US disclosed
CN-107208279-B Etching solution, replenishment solution, and method for forming copper wiring MEC股份有限公司 2021-03-26 CN disclosed
US-10174428-B2 Etchant, replenishment solution and method for forming copper wiring MEC COMPANY LTD. (JP) 2019-01-08 US disclosed
US-20170260632-A1 ETCHANT, REPLENISHMENT SOLUTION AND METHOD FOR FORMING COPPER WIRING MEC COMPANY LTD. (JP) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240245670-A1 DOSING REGIMEN AND PHARMACEUTICAL COMBINATION COMPRISING 3-(1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES IKZF1, IKZF2, IKZF3 DRD4 3620/4885DRD3 4024/4885DRD2 3504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.