SCHEMBL19328396

SCHEMBL19328396

BrCc1ccc(CBr)c2nsnc12

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HIF1A Q16665 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CCR1 P32246 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1354662 0.89 KDM4E (0.40) MAPTKDM4E
SCHEMBL2805013 0.78 KDM4E (0.52) MAPTKDM4EHIF1AHSD17B10MEN1
SCHEMBL12174042 0.74 KMT2A (0.38) MAPTKDM4EHIF1AHSD17B10MEN1
SCHEMBL24804038 0.66 KDM4E (0.44) KDM4EHSD17B10
SCHEMBL4158272 0.64 TRPA1 (0.35)
SCHEMBL7777200 0.64 TRPA1 (0.35)
SCHEMBL4158266 0.64 TRPA1 (0.35)
SCHEMBL21979136 0.62 MAPK1 (0.33) MAPTMEN1KMT2A
SCHEMBL30901339 0.62 MAPK1 (0.33) MAPTMEN1KMT2A
SCHEMBL31682523 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10147553-B2 Hydrophilic conjugated polymers, and methods of preparation and use thereof UNIVERSITY OF MASSACHUSETTS (US) 2018-12-04 US disclosed
US-20170263385-A1 HYDROPHILIC CONJUGATED POLYMERS, AND METHODS OF PREPARATION AND USE THEREOF NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2017-09-14 US disclosed
US-20170263385-A1 HYDROPHILIC CONJUGATED POLYMERS, AND METHODS OF PREPARATION AND USE THEREOF NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2017-09-14 US disclosed
US-20170263385-A1 HYDROPHILIC CONJUGATED POLYMERS, AND METHODS OF PREPARATION AND USE THEREOF NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2017-09-14 US disclosed