Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 6/20 | 0.37 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329672 | 1.00 | CYP19A1 (0.38) | CYP19A1TSHRHSD17B10GRM5PLAUR | |
| SCHEMBL19329642 | 0.84 | TLR8 (0.39) | TSHRHSD17B10 | |
| SCHEMBL19330015 | 0.83 | OXER1 (0.47) | — | |
| SCHEMBL19329633 | 0.83 | OXER1 (0.47) | — | |
| SCHEMBL19329879 | 0.81 | PDE10A (0.44) | CYP19A1 | |
| SCHEMBL1313567 | 0.77 | TSHR (0.46) | CYP19A1TSHRHSD17B10CDC7 | |
| SCHEMBL28390643 | 0.74 | PLAUR (0.57) | CYP19A1GRM5PLAURSLC11A2CDC7 | |
| SCHEMBL19329739 | 0.72 | OXER1 (0.48) | CYP19A1 | |
| SCHEMBL31573826 | 0.71 | GRM5 (0.47) | GRM5PLAURHRH1HTR6SLC11A2 | |
| SCHEMBL29387648 | 0.68 | CDC7 (0.64) | CYP19A1GRM5CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10940468-B2 | Nickel catalyst, process for preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-03-09 | — | — | US | disclosed |
| WO-2017154022-A1 | NOVEL NICKEL CATALYST, PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10940468-B2 | Nickel catalyst, process for preparation and use thereof | NISCH, NIT2, C9 | CYP19A1 84/4885TSHR 4602/4885HSD17B10 929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.