Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 9/20 | 0.64 |
| ▸ | CDK2 | P24941 | 4/20 | 0.51 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.50 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329863 | 1.00 | CDC7 (0.64) | CDC7CDK2ENPP3MAP3K14GRM5 | |
| SCHEMBL28562388 | 0.84 | CDC7 (0.60) | CDC7CDK2ENPP3MAP3K14KDM4E | |
| SCHEMBL30569112 | 0.79 | IRAK4 (0.44) | CDC7GRM5 | |
| SCHEMBL23795467 | 0.78 | CDC7 (0.72) | CDC7CDK2ENPP3MAP3K14CYP19A1 | |
| SCHEMBL18585951 | 0.78 | CDC7 (1.00) | CDC7CDK2MAP3K14 | |
| SCHEMBL31735499 | 0.78 | MAPT (0.48) | CDC7CDK2KDM4EALDH1A1 | |
| SCHEMBL20784111 | 0.78 | MAPT (0.48) | CDC7CDK2KDM4EALDH1A1 | |
| SCHEMBL29388268 | 0.78 | ROCK1 (0.47) | CDC7CDK2MAP3K14KDM4EALDH1A1 | |
| SCHEMBL23051698 | 0.78 | MAPT (0.48) | CDC7CDK2GRM5 | |
| SCHEMBL29388217 | 0.78 | MAPT (0.48) | CDC7CDK2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214252-B | Synthesis method of 6-phenyl-7- (pyridine-2-yl) -7H-indolo [2,3-c ] quinoline compound | 常州大学 | 2022-02-11 | — | — | CN | disclosed |