Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329647 | 0.89 | CYP19A1 (0.41) | CYP19A1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL19329745 | 0.86 | CYP19A1 (0.45) | CYP19A1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4865308 | 0.76 | SMN1; SMN2 (0.43) | NPSR1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL29387435 | 0.76 | SMN1; SMN2 (0.43) | NPSR1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL28487805 | 0.73 | MEN1 (0.38) | CYP19A1NPSR1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19329633 | 0.73 | OXER1 (0.47) | ALDH1A1KDM4EHPGD | |
| SCHEMBL19330015 | 0.73 | OXER1 (0.47) | ALDH1A1KDM4EHPGD | |
| SCHEMBL30865942 | 0.70 | HSD17B10 (0.44) | NPSR1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30724191 | 0.70 | POLB (0.41) | NPSR1ALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL30724190 | 0.70 | POLB (0.41) | NPSR1ALDH1A1KDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10940468-B2 | Nickel catalyst, process for preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-03-09 | — | — | US | disclosed |
| WO-2017154022-A1 | NOVEL NICKEL CATALYST, PROCESS FOR PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10940468-B2 | Nickel catalyst, process for preparation and use thereof | NISCH, NIT2, C9 | CYP19A1 84/4885NPSR1 1526/4885ALDH1A1 2645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.