Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387435 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EALDH1A1SLC6A2MEN1 | |
| SCHEMBL29155265 | 0.89 | POLB (0.38) | SMN1; SMN2KDM4EALDH1A1SLC6A2MEN1 | |
| SCHEMBL29134581 | 0.83 | MAPK14 (0.40) | SMN1; SMN2KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL29134984 | 0.83 | MAT2A (0.50) | SMN1; SMN2KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL30704300 | 0.83 | MAPK14 (0.40) | SMN1; SMN2KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL30704311 | 0.83 | MAT2A (0.50) | SMN1; SMN2KDM4EALDH1A1MEN1NPC1 | |
| SCHEMBL28492642 | 0.82 | SLC6A2 (0.45) | KDM4EALDH1A1SLC6A2MAPTKMT2A | |
| SCHEMBL30724191 | 0.79 | POLB (0.41) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL30724190 | 0.79 | POLB (0.41) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29408795 | 0.79 | POLB (0.41) | SMN1; SMN2KDM4EALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | claimed |
| CN-117343043-A | Synthesis method of 2-tridentate methyl-1- (pyridine-2-yl) indole compound | 山西天宏达安医药科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117384133-A | 2-bromo-1- (pyridin-2-yl) indole compound and preparation method thereof | 内蒙古益泽制药有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343043-A | Synthesis method of 2-tridentate methyl-1- (pyridine-2-yl) indole compound | 山西天宏达安医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343093-A | Synthesis method of iron-catalyzed non-activated gem difluoro-bialkylene compound double-silicon-based | 山西天宏达安医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343044-A | Synthesis method of 2-methyl-1- (pyridine-2-yl) indole compound | 太原理工大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343043-A | Synthesis method of 2-tridentate methyl-1- (pyridine-2-yl) indole compound | 山西天宏达安医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117343043-A | Synthesis method of 2-tridentate methyl-1- (pyridine-2-yl) indole compound | 山西天宏达安医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-1609101-B | Organometallic complex and light-emitting element containing the same | SEMICONDUCTOR ENERGY LAB | 2010-05-26 | — | — | CN | disclosed |
| US-7314769-B2 | Organometallic complex and light-emitting element containing the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-6998492-B2 | Organometallic complex and light-emitting element containing the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2006-02-14 | — | — | US | disclosed |
| CN-1609101-A | Organometallic complex and light-emitting element containing the same | SEMICONDUCTOR ENERGY LAB (JP) | 2005-04-27 | — | — | CN | disclosed |
| US-20050033054-A1 | Organometallic complex and light-emitting element containing the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2005-02-10 | — | — | US | disclosed |
| US-20040230061-A1 | Organometallic complex and light-emitting element containing the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033054-A1 | Organometallic complex and light-emitting element containing the same | BCKDK, CCNK, CDK20 | SMN1; SMN2 4825/4885KDM4E 463/4885ALDH1A1 355/4885 |
| US-20040230061-A1 | Organometallic complex and light-emitting element containing the same | NR0B1, BCKDK, NR4A1 | SMN1; SMN2 4808/4885KDM4E 384/4885ALDH1A1 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.