SCHEMBL19329931

SCHEMBL19329931

Oc1ccc(C(O)CNCCCC2CC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.47
▸ HIF1A Q16665 3/20 0.47
▸ TAAR1 Q96RJ0 3/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ KDM4E B2RXH2 2/20 0.47
▸ HTR1A P08908 1/20 0.47
▸ THPO P40225 1/20 0.47
▸ BLM P54132 1/20 0.47
▸ NMUR2 Q9GZQ4 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ ADRB2 P07550 7/20 0.44
▸ ADRB1 P08588 2/20 0.44
▸ TSHR P16473 2/20 0.44
▸ NFKB1 P19838 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ SLC22A1 O15245 1/20 0.44
▸ CHRM2 P08172 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19329940 0.93 ALDH1A1 (0.44) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E
Acetic Acid SCHEMBL19329768 0.92 ALDH1A1 (0.46) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E
SCHEMBL19330017 0.91 HIF1A (0.50) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E
SCHEMBL19329904 0.84 KDM4E (0.46) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E
SCHEMBL19330010 0.82 HIF1A (0.55) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E
SCHEMBL19329754 0.80 SMN1; SMN2 (0.54) ALDH1A1SMN1; SMN2KDM4EADRB2ADRB1
SCHEMBL19329770 0.79 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2KDM4ETDP1ADRB2
SCHEMBL19329755 0.78 ALDH1A1 (0.50) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E
Bamethan SCHEMBL120958 0.78 ALDH1A1 (0.58) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E
Bamethan SCHEMBL19329744 0.78 ALDH1A1 (0.58) ALDH1A1HIF1ATAAR1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2019-04-25 — — US claimed
EP-3426239-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA Atrogi AB (SE) 2019-01-16 — — EP claimed
WO-2017153737-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2017-09-14 — — WO claimed
EP-4676481-A1 COMBINATION OF BETA-2-ADRENERGIC RECEPTOR AGONISTS AND GLP-1 RECEPTOR AGONISTS FOR USE IN TREATING HYPERGLYCAEMIA Atrogi AB (SE) 2026-01-14 — — EP disclosed
EP-4665321-A1 COMBINATIONS OF BETA 2-ADRENERGIC RECEPTOR AGONISTS AND METFORMIN FOR USE IN TREATING OBESITY AND REDUCING BODY FAT Atrogi AB (SE) 2025-12-24 — — EP disclosed
EP-4651867-A1 BETA 2-ADRENERGIC RECEPTOR AGONISTS FOR TREATMENT OR PREVENTION OF MUSCLE WASTING Atrogi AB (SE) 2025-11-26 — — EP disclosed
WO-2024184408-A1 COMBINATION OF BETA-2-ADRENERGIC RECEPTOR AGONISTS AND GLP-1 RECEPTOR AGONISTS FOR USE IN TREATING HYPERGLYCAEMIA ATROGI AB (SE) 2024-09-12 — — WO disclosed
WO-2024170727-A1 COMBINATIONS OF BETA 2-ADRENERGIC RECEPTOR AGONISTS AND METFORMIN FOR USE IN TREATING OBESITY AND REDUCING BODY FAT ATROGI AB (SE) 2024-08-22 — — WO disclosed
WO-2024153813-A1 BETA 2-ADRENERGIC RECEPTOR AGONISTS FOR TREATMENT OR PREVENTION OF MUSCLE WASTING ATROGI AB (SE) 2024-07-25 — — WO disclosed
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2019-04-25 — — US disclosed
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2019-04-25 — — US disclosed
WO-2019053428-A1 BETA-HYDROXYETHYLAMINES FOR USE IN THE TREATMENT OR PREVENTION OF NON-ALCOHOLIC FATTY LIVER DISEASES ATROGI AB (SE) 2019-03-21 — — WO disclosed
WO-2019053428-A1 BETA-HYDROXYETHYLAMINES FOR USE IN THE TREATMENT OR PREVENTION OF NON-ALCOHOLIC FATTY LIVER DISEASES ATROGI AB (SE) 2019-03-21 — — WO disclosed
EP-3426239-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA Atrogi AB (SE) 2019-01-16 — — EP disclosed
WO-2017153737-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2017-09-14 — — WO disclosed
WO-2017153737-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2017-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA SLC5A2, SLC5A1, SLC2A2 ALDH1A1 1292/4885HIF1A 527/4885TAAR1 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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