Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL27647115 | 0.87 | MAPT (0.43) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL31639150 | 0.86 | CA12 (0.42) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL27186573 | 0.83 | CA12 (0.40) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL20541572 | 0.83 | KDM4E (0.46) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL1342951 | 0.81 | AKR1C4 (0.42) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL29781380 | 0.81 | AKR1C4 (0.42) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL5115259 | 0.79 | KDM4E (0.44) | KDM4EKEAP1CA1CA2CA4 | |
| SCHEMBL29810948 | 0.78 | KDM4E (0.40) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL17030866 | 0.78 | KDM4E (0.40) | KDM4EGLAKEAP1CA12CA1 | |
| SCHEMBL19330633 | 0.78 | SOS1 (0.50) | KDM4EGLACA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090514-A1 | COVALENT SARM1 INHIBITORS | NURA BIO, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
| WO-2017155816-A1 | QUINAZOLINE COMPOUNDS USEFUL AS M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2017-09-14 | — | — | WO | disclosed |