Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28226170 | 0.87 | KDM4E (0.48) | KDM4EKEAP1NFE2L2ASPHKDM8 | |
| SCHEMBL4591061 | 0.83 | DGAT1 (0.42) | CES2CES1KMT2AMAPTALDH1A1 | |
| SCHEMBL3226637 | 0.83 | KEAP1 (0.44) | KDM4EKEAP1NFE2L2CES2CES1 | |
| SCHEMBL29706506 | 0.83 | KEAP1 (0.44) | KDM4EKEAP1NFE2L2CES2CES1 | |
| SCHEMBL8377311 | 0.83 | KDM4E (0.44) | KDM4EKEAP1NFE2L2CES2CES1 | |
| SCHEMBL29810948 | 0.82 | KDM4E (0.40) | KDM4EKEAP1NFE2L2ASPHKDM8 | |
| SCHEMBL21415507 | 0.82 | KDM4E (0.48) | KDM4EKEAP1NFE2L2ASPHKDM8 | |
| SCHEMBL17030866 | 0.82 | KDM4E (0.40) | KDM4EKEAP1NFE2L2ASPHKDM8 | |
| SCHEMBL4502539 | 0.82 | KEAP1 (0.47) | KDM4EKEAP1NFE2L2CES2CES1 | |
| SCHEMBL503374 | 0.79 | KEAP1 (0.47) | KDM4EKEAP1NFE2L2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113604194-A | Modified epoxy resin binder for stone and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-11-05 | — | — | CN | claimed |
| CN-113583606-A | Stone binder of polyphenyl ether modified epoxy resin and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-113528068-A | Double-component stone crack sealer and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-10-22 | — | — | CN | claimed |
| CN-113462338-A | Stone binder and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-113403015-A | Double-component stone binder and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-09-17 | — | — | CN | claimed |
| EP-0968994-B1 | PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF | UBE INDUSTRIES (JP) | 2002-11-06 | — | — | EP | claimed |
| US-6160171-A | Trifluoro-substituted benzoic acid, esters thereof, and process for producing the same | UBE INDUSTRIES, LTD. (JP) | 2000-12-12 | — | — | US | claimed |
| EP-0968994-A1 | SUBSTITUTED TRIFLUOROBENZOIC ACIDS, ESTERS THEREOF, AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES, LTD. (JP) | 2000-01-05 | — | — | EP | claimed |
| JP-2178254-A | — | — | None | — | — | JP | disclosed |
| US-20220348558-A1 | INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES | UT RESEARCH FOUNDATION | 2022-11-03 | — | — | US | disclosed |
| CN-113604194-A | Modified epoxy resin binder for stone and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-11-05 | — | — | CN | disclosed |
| CN-113583606-A | Stone binder of polyphenyl ether modified epoxy resin and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113528068-A | Double-component stone crack sealer and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113462338-A | Stone binder and preparation method thereof | 湖南柯盛新材料有限公司 | 2021-10-01 | — | — | CN | disclosed |
| EP-0968994-B1 | PROCESS FOR PRODUCING SUBSTITUTED TRIFLUOROBENZOIC ACIDS AND ESTERS THEREOF | UBE INDUSTRIES (JP) | 2002-11-06 | — | — | EP | disclosed |
| WO-2002050019-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA CO. (US) | 2002-06-27 | — | — | WO | disclosed |
| US-6307091-B1 | TRIFLUOROMETHYLATING A TRIFLUOROIODOBENZOIC ACID ESTER WITH ADIFLUORO(FLUOROSULFONYL)ACETIC ACID ESTER IN THE PRESENCE OF A COPPER CATALYST IN AN ORGANIC SOLVENT. | UBE INDUSTRIES, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| US-6160171-A | Trifluoro-substituted benzoic acid, esters thereof, and process for producing the same | UBE INDUSTRIES, LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0968994-A1 | SUBSTITUTED TRIFLUOROBENZOIC ACIDS, ESTERS THEREOF, AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES, LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| JP-H02178254-A | IMPROVED SYNTHESIS OF 3-CHLORO-2,4,5-TRIFLUOROBENZOIC ACID | WARNER LAMBERT CO | 1990-07-11 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220348558-A1 | INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES | NEFM, EIF2AK2, PMP22 | KDM4E 3589/4885KEAP1 2170/4885NFE2L2 2198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.