Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15624090 | 0.95 | PKM (0.53) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL925757 | 0.90 | PKM (0.53) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL27519797 | 0.84 | PKM (0.58) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL3317094 | 0.79 | PKM (0.57) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL13625328 | 0.77 | PKM (0.72) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL1932281 | 0.75 | PKM (0.65) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL4537090 | 0.74 | PKM (0.59) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL29836465 | 0.72 | PKM (0.45) | PKMALDH1A1HTTPOLBKMT2A | |
| SCHEMBL20390807 | 0.72 | PKM (0.60) | PKMALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL29919528 | 0.72 | GPBAR1 (0.58) | PKMALDH1A1HTTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506970-A1 | SURFACTANT-ENABLED TRANSITION METAL-CATALYZED CHEMISTRY | Mycell Holdings Limited (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068895-A1 | SURFACTANT-ENABLED TRANSITION METAL-CATALYZED CHEMISTRY | MyCell Holdings Limited (US) | 2011-06-09 | — | — | WO | disclosed |