Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140642 | 0.84 | ALOX5 (0.44) | ALOX5KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL755753 | 0.76 | ALOX5 (0.47) | ALOX5KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL890162 | 0.76 | ALOX5 (0.47) | ALOX5KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL19578288 | 0.75 | ALOX5 (0.42) | ALOX5KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL13748245 | 0.74 | ALOX5 (0.54) | ALOX5KDM4EMEN1NPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3892301 | 0.74 | ALOX5 (0.46) | ALOX5KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL888872 | 0.73 | ALOX5 (0.49) | ALOX5KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL22361412 | 0.72 | ALOX5 (0.44) | ALOX5KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL26488237 | 0.71 | HDAC1 (0.40) | ALOX5HDAC3NPC1LMNAKMT2A | |
| SCHEMBL19334127 | 0.71 | ALOX5 (0.46) | ALOX5HDAC3ALDH1A1TDP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758487-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |