⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19373617 | 0.86 | EPHX1 (0.32) | — | |
| SCHEMBL25069337 | 0.84 | — | — | |
| SCHEMBL19570444 | 0.83 | GAA (0.30) | — | |
| SCHEMBL25069256 | 0.82 | — | — | |
| SCHEMBL23084757 | 0.78 | — | — | |
| SCHEMBL19334587 | 0.78 | — | — | |
| SCHEMBL22507922 | 0.76 | EPHX1 (0.38) | — | |
| SCHEMBL7778181 | 0.74 | ALDH1A1 (0.40) | — | |
| SCHEMBL4145396 | 0.74 | — | — | |
| SCHEMBL27112898 | 0.72 | EPHX1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058189-A1 | QUINOLIN-4-ONE AND 4(1H)-CINNOLINONE COMPOUNDS AND METHODS OF USING SAME | Frequency Therapeutics, Inc. (US) | 2023-02-23 | — | — | US | disclosed |
| US-20210070703-A1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | UNIV DREXEL (US) | 2021-03-11 | — | — | US | disclosed |
| US-9758477-B2 | Sulfamoylbenzamide derivatives as antiviral agents against HBV infection | DREXEL UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |