Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.63 |
| ▸ | TDO2 | P48775 | 4/20 | 0.63 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832651 | 0.79 | IDO1 (0.57) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL12597549 | 0.79 | IDO1 (0.59) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL5286855 | 0.78 | IDO1 (1.00) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL5528789 | 0.78 | IDO1 (1.00) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL31265741 | 0.78 | IDO1 (1.00) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL1226606 | 0.78 | IDO1 (1.00) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL31550888 | 0.78 | IDO1 (1.00) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL2983658 | 0.78 | IDO1 (0.61) | IDO1TDO2GSK3BMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9818269 | 0.77 | IDO1 (0.97) | IDO1TDO2GSK3BMAPTKDM4E | |
| SCHEMBL1461848 | 0.75 | IDO1 (0.64) | IDO1TDO2GSK3BMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758481-B2 | Targeting of EWS-FLI1 as anti-tumor therapy | GEORGETOWN UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |