SCHEMBL5286855

SCHEMBL5286855

NC(CC1C(=O)Nc2ccccc21)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 10/20 1.00
TDO2 P48775 4/20 1.00
GSK3B P49841 2/20 0.50
EGFR P00533 3/20 0.46
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SRC P12931 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1226606 1.00 IDO1 (1.00) IDO1TDO2GSK3BEGFRMAPT
SCHEMBL31550888 1.00 IDO1 (1.00) IDO1TDO2GSK3BEGFRMAPT
SCHEMBL31265741 1.00 IDO1 (1.00) IDO1TDO2GSK3BEGFRMAPT
SCHEMBL5528789 1.00 IDO1 (1.00) IDO1TDO2GSK3BEGFRMAPT
Hydrochloric Acid SCHEMBL9818269 0.99 IDO1 (0.97) IDO1TDO2GSK3BEGFRMAPT
SCHEMBL24740358 0.88 IDO1 (1.00) IDO1TDO2GSK3BEGFRMAPT
Hydrochloric Acid SCHEMBL25245762 0.87 IDO1 (0.97) IDO1TDO2GSK3BEGFRMAPT
SCHEMBL6507505 0.83 IDO1 (0.72) IDO1TDO2GSK3BEGFRMAPT
SCHEMBL25762243 0.82 IDO1 (0.70) IDO1TDO2GSK3BEGFRMAPT
SCHEMBL1520161 0.82 IDO1 (0.69) IDO1TDO2GSK3BEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
US-20260029406-A1 PROTEIN IDENTIFICATION VIA PEPTIDE BARCODES Quantum-Si Incorporated (US) 2026-01-29 US disclosed
US-20260023081-A1 SOLID PHASE LIBRARY PREPARATION FOR POLYPEPTIDE SEQUENCING Quantum-Si Incorporated (US) 2026-01-22 US disclosed
US-20260016481-A1 POLYPEPTIDE SEQUENCING REAGENTS AND METHODS OF USE Quantum-Si Incorporated (US) 2026-01-15 US disclosed
US-20250369978-A1 POLYPEPTIDE CLEAVING REAGENTS AND USES THEREOF Quantum-Si Incorporated (US) 2025-12-04 US disclosed
US-20250341526-A1 NOVEL DYES Quantum-Si Incorporated (US) 2025-11-06 US disclosed
EP-4605526-A1 POLYPEPTIDE CLEAVING REAGENTS AND USES THEREOF Quantum-Si Incorporated (US) 2025-08-27 EP disclosed
EP-4605011-A2 POLYPEPTIDYL LINKERS Quantum-Si Incorporated (US) 2025-08-27 EP disclosed
CN-119998660-A Compositions and methods for polypeptide analysis 宽腾矽公司 2025-05-13 CN disclosed
WO-2025024572-A1 PROTEIN QUANTIFICATION, TRACKING, AND IDENTIFICATION VIA PEPTIDE BARCODES Quantum-Si Incorporated (US) 2025-01-30 WO disclosed
US-20040147483-A1 Peptide inhibitors of hepatitis C virus NS3 protease PRIESTLEY E SCOTT (DE) 2004-07-29 US disclosed
US-6699855-B2 PYRROLOPYRAZINONES USEFUL AS SERINE PROTEASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2004-03-02 US disclosed
EP-1261611-A2 INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE Bristol-Myers Squibb Pharma Company (US) 2002-12-04 EP disclosed
US-20020177725-A1 Peptide inhibitors of hepatitis C virus NS3 protein BRISTOL-MYERS SQUIBB COMPANY (FORMERLY D/B/A DUPONT PHARMACEUTICALS COMPANY) 2002-11-28 US disclosed
US-20020123468-A1 Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-09-05 US disclosed
US-20020065248-A1 Inhibitors of hepatitis C virus NS3 protease BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-05-30 US disclosed
WO-2001064678-A2 INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-09-07 WO disclosed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US disclosed
EP-0787010-A1 AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-06 EP disclosed
WO-1996012499-A1 AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-05-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260016481-A1 POLYPEPTIDE SEQUENCING REAGENTS AND METHODS OF USE ARGLU1, SPPL2B, QPCTL IDO1 2612/4885TDO2 4263/4885GSK3B 3822/4885
US-20020065248-A1 Inhibitors of hepatitis C virus NS3 protease TMPRSS15, CTRC, CPN1 IDO1 1672/4885TDO2 3396/4885GSK3B 3097/4885
US-20020177725-A1 Peptide inhibitors of hepatitis C virus NS3 protein VIP, PRSS1, SERPINB1 IDO1 1004/4885TDO2 4501/4885GSK3B 1846/4885
US-20260029406-A1 PROTEIN IDENTIFICATION VIA PEPTIDE BARCODES MAX, DNMT3A, SET IDO1 4092/4885TDO2 4362/4885GSK3B 4012/4885
US-20040147483-A1 Peptide inhibitors of hepatitis C virus NS3 protease VIP, PRSS1, CTSC IDO1 851/4885TDO2 4508/4885GSK3B 2064/4885
US-20260023081-A1 SOLID PHASE LIBRARY PREPARATION FOR POLYPEPTIDE SEQUENCING SPPL2B, SPPL2A, CTRC IDO1 1868/4885TDO2 1618/4885GSK3B 3798/4885
US-20020123468-A1 Alpha-ketoamide inhibitors of hepatitis C virus NS3 protease CES1, CYP51A1, SPINT2 IDO1 525/4885TDO2 2629/4885GSK3B 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.