Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 17/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.48 |
| ▸ | CLK2 | P49760 | 4/20 | 0.41 |
| ▸ | CLK3 | P49761 | 4/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179074 | 0.92 | WNT1 (0.52) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL19335949 | 0.90 | WNT1 (0.48) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL19336089 | 0.90 | WNT1 (0.53) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL19860618 | 0.89 | CLK2 (0.53) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17571508 | 0.89 | WNT1 (0.53) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL20992912 | 0.88 | CLK2 (0.49) | WNT1CLK2CLK3DYRK1A | |
| SCHEMBL17571528 | 0.86 | WNT1 (0.58) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL19336052 | 0.86 | WNT1 (0.63) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17571507 | 0.85 | WNT1 (0.55) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17571531 | 0.85 | WNT1 (0.53) | WNT1TGFBR1CLK2CLK3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758531-B2 | 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-09-12 | — | — | US | disclosed |