Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 11/20 | 0.51 |
| ▸ | CCND1 | P24385 | 11/20 | 0.51 |
| ▸ | CDK2 | P24941 | 18/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18637985 | 0.81 | MAPK8 (0.52) | CDK4CCND1CDK2CCNE1 | |
| SCHEMBL15298054 | 0.81 | MAPK8 (0.52) | CDK4CCND1CDK2CCNE1 | |
| SCHEMBL18637767 | 0.74 | CCND1 (0.53) | CDK4CCND1CDK2CCNE1 | |
| SCHEMBL22570031 | 0.72 | CCND1 (0.50) | CDK4CCND1CDK2CCNE1 | |
| SCHEMBL16088345 | 0.71 | CDK4 (0.51) | CDK4CCND1 | |
| SCHEMBL22569976 | 0.70 | CDK4 (0.48) | CDK4CCND1 | |
| SCHEMBL22569977 | 0.70 | CDK4 (0.48) | CDK4CCND1 | |
| SCHEMBL22570084 | 0.70 | CDK4 (0.48) | CDK4CCND1 | |
| SCHEMBL22570038 | 0.69 | MAPK1 (0.53) | CDK4CCND1 | |
| SCHEMBL22570028 | 0.69 | CDK4 (0.52) | CDK4CCND1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216792-A1 | LACTAM KINASE INHIBITORS | Tavares, Francis Xavier (US) | 2017-09-13 | — | — | EP | disclosed |