Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13642453 | 0.88 | USP30 (0.49) | USP30SCN9AGPR119CSF1RKDR | |
| SCHEMBL2146881 | 0.85 | USP30 (0.47) | USP30SCN9AGPR119CSF1RKDR | |
| SCHEMBL16520031 | 0.85 | GPR119 (0.53) | USP30SCN9AGPR119 | |
| SCHEMBL16520043 | 0.84 | USP30 (0.47) | USP30SCN9AGPR119CSF1RKDR | |
| SCHEMBL19336722 | 0.83 | SCN9A (0.48) | SCN9AGPR119CSF1RKDRCHEK2 | |
| SCHEMBL16688916 | 0.79 | USP30 (0.50) | USP30GPR119CSF1RAAK1FAAH | |
| SCHEMBL23122024 | 0.79 | USP30 (0.49) | USP30GPR119CSF1RAAK1 | |
| SCHEMBL18825434 | 0.79 | USP30 (0.49) | USP30SCN9AGPR119CSF1RAAK1 | |
| SCHEMBL23329734 | 0.78 | USP30 (0.50) | USP30GPR119AAK1FAAH | |
| SCHEMBL16520143 | 0.77 | USP30 (0.48) | USP30GPR119CSF1RAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2840083-B1 | NITROGENATED BICYCLIC AROMATIC HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC (JP) | 2017-09-13 | — | — | EP | disclosed |