Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 14/20 | 0.70 |
| ▸ | FYN | P06241 | 3/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445622 | 0.90 | TTK (0.78) | TTKFYNCACNA1HERN1 | |
| SCHEMBL17445624 | 0.86 | TTK (0.65) | TTKFYNCACNA1H | |
| SCHEMBL19336813 | 0.84 | TTK (0.65) | TTKFYNCACNA1H | |
| SCHEMBL15554470 | 0.83 | TTK (1.00) | TTK | |
| SCHEMBL19336855 | 0.82 | TTK (0.71) | TTKFYN | |
| SCHEMBL19336800 | 0.82 | TTK (0.83) | TTK | |
| SCHEMBL17425437 | 0.79 | TTK (0.76) | TTKFYN | |
| SCHEMBL456224 | 0.78 | TTK (0.78) | TTKFYN | |
| SCHEMBL458692 | 0.77 | TTK (0.76) | TTK | |
| SCHEMBL19336837 | 0.73 | TTK (0.67) | TTKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961752-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Pharma AG (DE) | 2017-09-13 | — | — | EP | disclosed |