Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 15/20 | 0.71 |
| ▸ | FYN | P06241 | 4/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17445626 | 0.90 | TTK (0.78) | TTKFYN | |
| SCHEMBL17445627 | 0.86 | TTK (0.66) | TTKFYN | |
| SCHEMBL19336831 | 0.84 | TTK (0.65) | TTKFYN | |
| SCHEMBL16001600 | 0.83 | TTK (1.00) | TTK | |
| SCHEMBL19336826 | 0.82 | TTK (0.70) | TTKFYN | |
| SCHEMBL19336837 | 0.82 | TTK (0.67) | TTKFYNPIM1 | |
| SCHEMBL17425437 | 0.76 | TTK (0.76) | TTKFYN | |
| SCHEMBL10279273 | 0.76 | TTK (0.71) | TTKFYN | |
| SCHEMBL456224 | 0.75 | TTK (0.78) | TTKFYN | |
| SCHEMBL458770 | 0.75 | TTK (0.74) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961752-B1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Pharma AG (DE) | 2017-09-13 | — | — | EP | disclosed |