Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17985339 | 0.90 | MEN1 (0.33) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL783565 | 0.90 | MAPT (0.34) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL802702 | 0.89 | MEN1 (0.36) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL15806152 | 0.88 | RXFP1 (0.34) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL16978573 | 0.88 | MAPT (0.33) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL19104499 | 0.88 | MAPT (0.33) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL16978582 | 0.88 | MAPT (0.33) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL15806083 | 0.88 | ALDH1A1 (0.34) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL802759 | 0.88 | MAPT (0.31) | MAPTKDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL803054 | 0.88 | MEN1 (0.40) | MAPTKDM4EALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931698-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-09-13 | — | — | EP | disclosed |