Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.39 |
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.39 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19336964 | 0.91 | CCNT1 (0.43) | CCNT1CDK9MAPK8GSK3BPTK2 | |
| SCHEMBL19337022 | 0.85 | EGFR (0.47) | ALKINSRKDRJAK3EGFR | |
| SCHEMBL32681522 | 0.80 | CCNT1 (0.42) | CCNT1CDK9MAPK8GSK3BGSK3A | |
| SCHEMBL22509271 | 0.79 | PTK2 (0.48) | CCNT1CDK9MAPK8GSK3BPTK2 | |
| SCHEMBL22994859 | 0.79 | CCNT1 (0.39) | CCNT1CDK9MAPK8GSK3BPTK2 | |
| SCHEMBL32681474 | 0.78 | KMT2A (0.46) | CCNT1CDK9MAPK8GSK3BGSK3A | |
| SCHEMBL19336965 | 0.76 | EGFR (0.48) | ALKINSRKDRJAK3EGFR | |
| SCHEMBL29597402 | 0.75 | KMT2A (0.47) | CCNT1CDK9MAPK1EGFRMEN1 | |
| SCHEMBL30948589 | 0.75 | CCNT1 (0.42) | CCNT1CDK9MAPK8GSK3BPTK2 | |
| SCHEMBL32681483 | 0.75 | KMT2A (0.41) | CCNT1CDK9GSK3BGSK3AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3216786-A1 | PYRIMIDINE OR PYRIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | Shanghai Shaletech Technology Co., Ltd. (CN) | 2017-09-13 | — | — | EP | disclosed |