Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 12/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 3/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | FLT3 | P36888 | 3/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | MELK | Q14680 | 3/20 | 0.45 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.45 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24240366 | 0.83 | EGFR (0.47) | PTK2JAK3INSRKDRALK | |
| SCHEMBL19336964 | 0.81 | CCNT1 (0.43) | PTK2FGFR1FGFR3FGFR2FGFR4 | |
| SCHEMBL19337026 | 0.79 | CCNT1 (0.41) | PTK2FGFR1FGFR3CDC7DAPK3 | |
| SCHEMBL17059353 | 0.78 | PIN1 (0.40) | PTK2FGFR1FGFR3FGFR2FGFR4 | |
| SCHEMBL29597402 | 0.77 | KMT2A (0.47) | MAPK1ABCG2CDK9CCNT1NPC1 | |
| SCHEMBL26324473 | 0.77 | LRRK2 (0.39) | PTK2ABCG2KMT2A | |
| SCHEMBL18607073 | 0.76 | MAPK10 (0.48) | PTK2FGFR1FGFR3CDC7DAPK3 | |
| SCHEMBL22994835 | 0.75 | LRRK2 (0.43) | PTK2FGFR1FGFR3CDC7DAPK3 | |
| SCHEMBL17059224 | 0.75 | IGF1R (0.43) | FGFR1FGFR3FGFR2FGFR4CDK2 | |
| SCHEMBL18011894 | 0.75 | MAPK8 (0.52) | PTK2FGFR1FGFR3CDC7DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020200158-A1 | N-HETEROAROMATIC AMIDE DERIVATIVES FOR TREATMENT OF CANCER | 深圳福沃药业有限公司 | 2020-10-08 | — | — | WO | disclosed |