Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11718323 | 0.82 | GAA (0.65) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL7633120 | 0.79 | ALDH1A1 (0.47) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL1680531 | 0.79 | GAA (0.67) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL28290300 | 0.77 | MGAM (0.50) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL5691153 | 0.77 | GAA (0.64) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL29403798 | 0.77 | GAA (0.64) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL28290424 | 0.77 | MGAM (0.50) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL9177680 | 0.77 | GAA (0.64) | GLO1MGAMGAASIMGAM2 | |
| SCHEMBL626011 | 0.77 | GAA (0.64) | GLO1MGAMGAASIMGAM2 | |
| Ethyl Acetate SCHEMBL28822002 | 0.77 | ALDH1A1 (0.54) | GLO1MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010901-B1 | HETEROARYL SUBSTITUTED PYRAZOLES | Bayer Pharma AG (DE) | 2017-09-13 | — | — | EP | disclosed |