⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991720 | 0.83 | — | — | |
| SCHEMBL4290336 | 0.81 | — | — | |
| SCHEMBL11026095 | 0.78 | LMNA (0.30) | — | |
| SCHEMBL10753969 | 0.77 | — | — | |
| SCHEMBL19383834 | 0.77 | — | — | |
| Tert-Butylamine SCHEMBL20505712 | 0.76 | TP53 (0.61) | — | |
| Tert-Butylamine SCHEMBL5505705 | 0.76 | TP53 (0.61) | — | |
| SCHEMBL15187927 | 0.75 | — | — | |
| SCHEMBL22667910 | 0.75 | — | — | |
| SCHEMBL19557676 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368010-A | Process for the preparation of 2,3,3, 3-tetrafluoro-1-propene and recycling of impurity-free 2-chloro-3, 3, 3-trifluoropropene | 阿科玛法国公司 | 2018-08-03 | — | — | CN | claimed |
| CN-102633783-A | Benzazole derivatives, compositions, and methods of use as aurora kinase inhibitors | TRANSTECH PHARMA INC | 2012-08-15 | — | — | CN | claimed |
| EP-2205351-A2 | HYDROPROCESSING BULK CATALYST AND USES THEREOF | Chevron U.S.A., Inc. (US) | 2010-07-14 | — | — | EP | claimed |
| EP-2134722-A1 | WORTMANNIN-RAPALOG CONJUGATE AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2009-12-23 | — | — | EP | claimed |
| EP-2132212-A1 | WORTMANNIN-RAPAMYCIN CONJUGATE AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2009-12-16 | — | — | EP | claimed |
| WO-2009058861-A2 | HYDROPROCESSING BULK CATALYST AND USES THEREOF | CHEVRON U.S.A. INC. (US) | 2009-05-07 | — | — | WO | claimed |
| WO-2008124026-A1 | WORTMANNIN-RAPAMYCIN CONJUGATE AND USES THEREOF | WYETH (US) | 2008-10-16 | — | — | WO | claimed |
| WO-2008124020-A1 | WORTMANNIN-RAPALOG CONJUGATE AND USES THEREOF | WYETH (US) | 2008-10-16 | — | — | WO | claimed |
| CN-118239953-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2024-06-25 | — | — | CN | disclosed |
| CN-117185976-A | Synthesis method of compound L635 | 深圳市灵兰生物医药科技有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023209375-A1 | USE AND METHOD | INNOSPEC LIMITED (GB) | 2023-11-02 | — | — | WO | disclosed |
| WO-2023209374-A1 | USE AND METHOD | INNOSPEC LIMITED (GB) | 2023-11-02 | — | — | WO | disclosed |
| CN-116157551-A | Silicon-based self-assembled monolayer composition and surface preparation using the same | 乔治洛德方法研究和开发液化空气有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-107850859-B | Stripping composition for removing photoresist on semiconductor substrate | 富士胶片电子材料美国有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-1213684-A | Chemical Mechanical Polishing Composition | CHANGXING CHEMICAL IND CO LTD (CN) | 1999-04-14 | — | — | CN | disclosed |
| WO-1999008779-A1 | METHOD OF CONVERTING AMINE HYDROHALIDE INTO FREE AMINE | PPG INDUSTRIES OHIO, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| WO-1999008778-A1 | METHOD OF CONVERTING AMINE HYDROHALIDE INTO FREE AMINE | PPG INDUSTRIES OHIO, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| EP-0210893-B1 | BENZAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR THERAPEUTICAL USE | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1990-10-03 | — | — | EP | disclosed |
| US-4703055-A | GASTROMOTOR AGENTS; NO SIDE EFFECTS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1987-10-27 | — | — | US | disclosed |
| EP-0210893-A1 | Benzamides, process for their preparation and their therapeutical use | Laboratoires DELAGRANGE, Société Anonyme (FR) | 1987-02-04 | — | — | EP | disclosed |