Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15319768 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| SCHEMBL15320174 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| SCHEMBL15320681 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| SCHEMBL16577001 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| SCHEMBL16577088 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| SCHEMBL19337815 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| SCHEMBL15320653 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| SCHEMBL15319999 | 1.00 | CCR2 (1.00) | CCR2CYP3A4KCNH2 | |
| Succinic Acid SCHEMBL15408481 | 0.96 | CCR2 (0.92) | CCR2CYP3A4KCNH2 | |
| SCHEMBL15424040 | 0.95 | CCR2 (0.91) | CCR2CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834234-B1 | FUSED CYCLOPENTYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-13 | — | — | EP | disclosed |