Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30154195 | 0.89 | CTSK (0.44) | CTSK | |
| SCHEMBL19337882 | 0.89 | CTSK (0.44) | CTSK | |
| SCHEMBL30136143 | 0.89 | CTSK (0.44) | CTSK | |
| SCHEMBL10270529 | 0.85 | CTSK (0.47) | CTSK | |
| SCHEMBL15797176 | 0.81 | CTSK (0.48) | CTSK | |
| SCHEMBL9943895 | 0.81 | CTSK (0.48) | CTSK | |
| SCHEMBL384990 | 0.81 | CTSK (0.48) | CTSK | |
| SCHEMBL384008 | 0.81 | CTSK (0.48) | CTSK | |
| SCHEMBL9102463 | 0.81 | CTSK (0.48) | CTSK | |
| SCHEMBL24963652 | 0.80 | CTSK (0.42) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834234-B1 | FUSED CYCLOPENTYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-13 | — | — | EP | disclosed |