Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 3/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2491763 | 0.72 | MET (0.47) | MET | |
| SCHEMBL2496459 | 0.71 | MET (0.59) | METERN1 | |
| SCHEMBL2494801 | 0.66 | CLK1 (0.42) | MAPTMETERN1 | |
| SCHEMBL2494891 | 0.65 | MET (0.65) | MET | |
| SCHEMBL2498747 | 0.61 | MET (0.39) | MAPTHSD17B10METERN1 | |
| SCHEMBL2492178 | 0.59 | HDAC3 (0.48) | MAPTHSD17B10ERN1 | |
| SCHEMBL17201672 | 0.58 | ERN1 (0.48) | MAPTHSD17B10ERN1 | |
| SCHEMBL2362973 | 0.57 | HDAC3 (0.51) | HSD17B10ERN1 | |
| SCHEMBL17201566 | 0.56 | HDAC3 (0.47) | MAPTHSD17B10ERN1 | |
| SCHEMBL7018973 | 0.56 | HDAC3 (0.73) | MAPTHSD17B10ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966214-B9 | TRIAZOLOPYRIDAZINES AS TYROSINE KINASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-13 | — | — | EP | disclosed |