Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14993412 | 1.00 | KDM4E (0.35) | KDM4ESMN1; SMN2MAPK1ALDH1A1NPSR1 | |
| SCHEMBL1297817 | 1.00 | KDM4E (0.35) | KDM4ESMN1; SMN2MAPK1ALDH1A1NPSR1 | |
| SCHEMBL15008153 | 1.00 | KDM4E (0.35) | KDM4ESMN1; SMN2MAPK1ALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL15008983 | 0.98 | KDM4E (0.36) | KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15008985 | 0.98 | KDM4E (0.36) | KDM4ESMN1; SMN2 | |
| SCHEMBL19338340 | 0.86 | CYP2A13 (0.33) | KDM4EMAPK1 | |
| SCHEMBL14995267 | 0.85 | KDM4E (0.33) | KDM4ESMN1; SMN2 | |
| SCHEMBL14995231 | 0.85 | KDM4E (0.33) | KDM4ESMN1; SMN2 | |
| SCHEMBL15009357 | 0.85 | KDM4E (0.33) | KDM4ESMN1; SMN2 | |
| SCHEMBL15025803 | 0.84 | SIGMAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785688-B1 | A PROCESS FOR THE MANUFACTURE OF CHIRAL CATALYSTS AND THEIR SALTS | SCINOPHARM TAIWAN LTD (TW) | 2017-09-13 | — | — | EP | disclosed |